Title: Prevalence of Aneurysmal and Solitary Bone Cysts in Young Patients
Authors: Zehetgruber H, Bittner B, Gruber D, Krepler P, Trieb K, Kotz R, Dominkus M
Source: Clinical Orthopedics and Related Research October 2005; 439:136-143
PODIATRIC RELEVANCE:
Aneurysmal bone cysts and solitary bone cysts are frequently seen in young patients, often as an incidental radiographic finding. Clinical, radiographic and morphologic appearance has been described in the literature. This article evaluates the prevalence and recurrence rate of these lesions.
METHODS:
A retrospective, population-based analysis of 141 surgically treated, histologically confirmed aneurysmal or solitary bone cysts was performed. Sixty-eight patients with solitary bone cysts and seventy-three patients with aneurysmal bone cysts were enrolled. All patients were adolescents under 20 years of age. Information recorded included: location, size of lesion, date of diagnosis, presence and duration of symptoms, type of treatment, gender and age.
Statistical models including the chi square test, Poisson regression model, and Cox regression model were used for analysis of gender difference, prevalence, and recurrence of these bone cysts.
RESULTS:
Both aneurysmal bone cysts and solitary bone cysts prevalence was influenced both by gender and age. Aneurysmal bone cysts had a 1.8:1 male to female ratio with a mean age of 11.1 years. The annual prevalence was 0.32 per 100,000 individuals. Solitary bone cysts had a 1.96:1 male to female ratio. The annual prevalence was 0.30. Increased risk of local recurrence is associated with male gender and young age.
COMMENTS:
Aneurysmal and solitary bone cysts are common bone lesions seen during skeletal growth. It is important to be aware of the lesions, their prevalence and recurrence rates as physicians. Thus far there has been little information published concerning the epidemiology of bone cysts. The true prevalence is difficult to obtain because many of these cysts regress spontaneously before diagnosis. Further study is warranted in the prevalence and recurrence of bone cysts.
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Disclaimer:
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